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  1. Sen S, Dodamani A and Nambiar M (2023) Emerging mechanisms and roles of meiotic crossover repression at centromeres. Current Topics Dev. Biol. 151:155-190.

  2. Hyppa RW*, Cho JD*, Nambiar M and Smith GR (2022) Redirecting meiotic DNA break hotspot determinant
    proteins alters localized spatial control of DNA break formation and repair. Nucleic Acids Res. 50 (2) 899-914     (*Equal first authors).

  3. Sarkar S and Nambiar M (2022) G‐quadruplexes in the mitochondrial genome – a cause for instability. FEBS J.  289 (1) 117-120. 

  4. Kumari R, Roy U, Desai S, Nilavar NM, Nieuwenhuijze AV, Paranjape A, Radha G, Bawa P, Srivastava M, Nambiar M, Balaji KN, Liston A, Choudhary B and Raghavan SC (2021) MicroRNA miR-29c regulates RAG1 expression and modulates V(D)J recombination during B cell development. Cell Rep. 36 (2) 109390.

  5. Smith GR and Nambiar M (2020) New Solutions to Old Problems: Molecular Mechanisms of Meiotic Crossover Control. Trends Genet. 36 (5) 337-346.

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Papers before joining IISER Pune

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  1. Nambiar M, Chuang YC and Smith GR (2019) Distributing meiotic crossovers for optimal fertility and evolution. DNA Repair 81 (102648).

  2. Nambiar M and Smith GR (2018) Pericentromere-specific cohesin complex prevents meiotic pericentric double-strand breaks and lethal crossovers. Mol. Cell  71 (4):540-553. 

  3. Vartak SV, Swarup HA, Gopalakrishnan V, Gopinatha VK, Ropars V, Nambiar M, John F, Kothanahally SKS, Kumari R, Kumari N, Ray U, Radha G, Dinesh D, Pandey M, Ananda H, Karki SS, Srivastava M, Charbonnier JB, Choudhary B, Mantelingu K, Raghavan SC. (2018) Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner. FEBS J. 285(21):3959-3976.

  4. Nambiar M and Smith GR (2016) Repression of harmful meiotic recombination in centromeric regions. Semin. Cell Dev. Biol. 54:188-97. 

  5. Ma L, Milman N, Nambiar M, Smith GR (2015) Two separable functions of Ctp1 in the early steps of meiotic DNA double-strand break repair. Nucleic Acids Res. 43 (15):7349-7359.

  6. Kumari R, Nambiar M, Shanbagh S, Raghavan SC (2015) Detection of G-quadruplex DNA using primer extension as a tool. PLoS ONE 10:e0119722.

  7. Nambiar M*, Srivastava M*, Gopalakrishnan V, Sankaran SK and Raghavan SC (2013) G-quadruplex structures formed at the HOX11 breakpoint region contribute to its fragility during t(10;14) translocation in T-Cell Leukemia. Mol. Cell. Biol. 33:4266-4281 (*Equal first authors). 

  8. Nambiar M and Raghavan SC (2013) Chromosomal translocations in healthy human beings: Implications in oncogenesis. Cell. Mol. Life Sciences 70:1381-92.

  9. Kavitha CV, Nambiar M, Narayanaswamy PB, Thomas E, Rathore U, Choudhary B, Rangappa KS, Raghavan SC (2013) Propyl-2-(8-(3,4-difluorobenzyl)-2',5'-dioxo-8-azaspiro[bicyclo[3.2.1]octane-3,4'-imidazolidine]-1'-yl) acetate induces apoptosis in human leukemia cells through mitochondrial pathway following cell cycle arrest.  PLoS ONE 8:e69103.

  10. Srivastava M, Nambiar M, Sharma S, Karki SS, Goldsmith G, Hegde M, Kumar S, Pandey M, Singh RK, Ray P, Natarajan R, Kelkar M, De A, Choudhary B, Raghavan SC (2012) An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression. Cell 151:1474-87.

  11. Nambiar M and Raghavan SC (2012) A novel mechanism of RAG cleavage induces breaks at BCL2 minor breakpoint cluster region during t(14;18) translocation in follicular lymphoma. J. Biol. Chem. 287 (12): 8688-701.

  12. Katapadi VK, Nambiar M, Raghavan SC (2012) Potential G-quadruplex formation at breakpoint regions of chromosomal translocations in cancer may explain their fragility. Genomics 100:72-80.

  13. Nambiar M and Raghavan SC (2011) How does DNA break during chromosomal translocations? Nucleic Acids Res. 39(14):5813-25.

  14. Nambiar M, Goldsmith G, Moorthy BT, Joshi MV, Choudhary B, Lieber MR, Hosur RV, Raghavan SC (2011) Characterization of G-quadruplex Structure at BCL2 Major Breakpoint Region of t(14;18) translocation in follicular lymphoma. Nucleic Acids Res. 39(3):936-48.

  15. Shahabuddin MS*, Nambiar M*, Moorthy BT, Naik PL, Choudhary B, Advirao GM, Raghavan SC (2011) A novel structural derivative of natural alkaloid ellipticine, MDPSQ, induces necrosis in leukemic cells. Invest. New Drugs 29(4):523-33 (*Equal first authors).

  16. Shahabuddin MS, Nambiar M, Advirao GM, Raghavan SC (2011) Intercalative pyrimido[4',5':4,5] thieno (2,3- b)quinolines induce apoptosis in leukemic cells: a comparative study of methoxy and morpholino substitution. Invest. New Drugs 29: 873-82.

  17. Karki SS, Panjamurthy K, Kumar S, Nambiar M, Ramareddy SA, Chiruvella KK, Raghavan SC (2011) Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4'-fluorophenyl)-imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent anticancer agents. Eur. J. Med. Chem. 46: 2109-16.

  18. Nambiar M and Raghavan SC (2010) Prevalence and analysis of t(14;18) t(11;14) chromosomal translocation in healthy individuals in Indian population. Annals Haematol. 89:35-43.

  19. Kumar TS*, Kari V*, Choudhary B*, Nambiar M, Akila TS, Raghavan SC (2010) Anti-apoptotic Protein, BCL2, Downregulates Nonhomologous DNA End Joining in Cancer Cells. J. Biol. Chem. 285(42):32657-32670 (*Equal first authors).

  20. Shahabuddin MS*, Nambiar M*, Choudhary B, Advirao GM, Raghavan SC (2010) A novel DNA intercalator, butylamino-pyrimido[4',5':4,5]selenolo(2,3-b)quinoline, induces cell cycle arrest and apoptosis in leukemic cells. Invest. New Drugs 28:35-48 (*Equal first authors).

  21. Chiruvella KK, Kari V, Choudhary B, Nambiar M, Ghanta RG, Raghavan SC (2008) Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells. FEBS Lett. 582(29):4066-76.

  22. Kavitha CV, Nambiar M, Ananda Kumar CS, Muniyappa K, Rangappa KS, Raghavan SC (2009) Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells. Biochem. Pharmacol. 77:348-363.

  23. Nambiar M, Kari V, Raghavan SC (2008) Chromosomal Translocations in Cancer. Biochim. Biophys. Acta Rev. Cancer 1786(2):139-152.

  24. Nambiar M, Choudhary B, Rao C, Raghavan SC (2008) Detection of Bcl-2/JH Chromosomal Translocations in Paraffin-Embedded Tissue of Follicular Lymphoma patients. Biomed. Materials 3(3):034103.

“If you can't explain it simply, you don't understand it well enough - A. Einstein”

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