We are broadly interested in understanding the molecular mechanisms underlying errors in chromosomal segregation during cell division. Using the genetically tractable fission yeast Schizosaccharomyces pombe as a model system, we investigate the role of recombination in generating errors during meiosis. We are also interested in exploring the molecular interactions between cohesins and heterochromatin at the centromeres in maintaining chromosomal segregation fidelity both in meiosis as well as during mitosis in cancer cells.  

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We use yeast genetics, cell and molecular biology, proteomics and biochemical approaches to decipher the mysteries of meiotic recombination and chromosomal segregation.